Differences in Cardiovascular Disease Risk Factors Associated With Maximum and Mean Carotid Intima-Media Thickness Among Hemodialysis Patients
Iranian Journal of Kidney Diseases, 05/08/2012
Nassiri AA et al. - The findings suggest that in dialysis patients, effects of cardiovascular risk factors on the mean and maximum Carotid intima-media thickness (CIMT) might be different.Methods
- The mean and the maximum CIMT were measured using a B-mode ultrasonography in 75 hemodialysis patients, and the correlation between CIMT and cardiovascular risk factors were assessed.
- The mean and maximum CIMT measurements were 0.5 mm (range, 0.2 mm to 1 mm) and 3.4 mm (1.4 mm to 5.6 mm), respectively.
- Among all the studied variables, age (P = .04, r = 0.238), HS-CRP (P = .01, r = 0.284), mean arterial blood pressure (P = .003, r = 0.343), and DM (P = .02) had significant correlations with the mean CIMT, while only age (P = .02, r = 0.473) and serum creatinine levels (P = .02, r = -0.493) were significantly associated with the maximum CIMT.
- A positive nonsignificant correlation was observed between the mean and maximum CIMT values (P = .08, R2 linear = 0.214).