Understanding the natural progression in %FEV1 decline in patients with cystic fibrosis: a longitudinal study
Thorax, 05/08/2012
Taylor–Robinson D et al. – This approach provides a more realistic estimate of the %FEV1 trajectory of people with chronic lung disease by acknowledging the imprecision in individual measurements and the correlation structure of repeated measurements on the same individual over time. This method has applications for clinicians in assessing prognosis and the need for treatment intensification, and for use in clinical trials.



