Sphingosine Analogue AAL-R Increases TLR7-Mediated Dendritic Cell Responses via p38 and Type I IFN Signaling Pathways Full Text
The Journal of Immunology, 05/16/2012
Seo YJ et al. – AAL–R activated p38 MAPK to increase type I IFN synthesis and TLR7–mediated DC maturation. These findings enhance the understanding of sphingosine regulation of the host immune system, in particular upon pathogenic infections.