The prevalence of mutations in KCNQ1, KCNH2, and SCN5A in an unselected national cohort of young sudden unexplained death cases
Journal of Cardiovascular Electrophysiology, 05/21/2012
Winkel BG et al. – In a nationwide setting, the genetic investigation of an unselected population of sudden unexplained death cases aged 1–35 years finds a lower than expected number of mutations compared to referred populations previously reported. Authors therefore conclude that the prevalence of mutations in the three major LQTS associated genes may not be as abundant as previously estimated.