Rapid spoligotyping of Mycobacterium tuberculosis complex bacteria using a microarray system with automatic data processing and assignment
Journal of Clinical Microbiology, 05/04/2012
Ruettger A et al. – Membrane–based spoligotyping has been converted to DNA microarray format to qualify it for high–throughput testing. Authors have shown the assay's validity, as well as its suitability for direct typing from tissue and detecting new spoligotypes. Advantages of the microarray methodology include rapidity, ease of operation, automatic data processing and affordability.