DNA and Modified Vaccinia Virus Ankara Vaccines Encoding Multiple Cytotoxic and Helper T-Lymphocyte Epitopes of Human Immunodeficiency Virus Type 1 (HIV-1) Are Safe but Weakly Immunogenic in HIV-1-Uninfected, Vaccinia Virus-Naive Adults
Clinical and Vaccine Immunology, 05/08/2012
Gorse GJ et al. – The peptide–based vaccines were safe but were ineffective at inducing HIV–1–specific immune responses and induced much weaker responses than MVA vaccines expressing the entire open reading frames of HIV–1 proteins.
