Systemic Up-Regulation of TLR4 Causes Lipopolysaccharide-Induced Augmentation of Nasal Cytokine Release in Allergic Rhinitis

International Archives of Allergy and Immunology, 05/03/2012

A systemic up–regulation of Toll–like receptors (TLRs) in symptomatic allergic rhinitis may explain why lipopolysaccharide (LPS) preceded by allergen increases nasal cytokine release.

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