Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations
British Journal of Cancer, 04/27/2012
Glauche I et al. – The authors modelling approach is a highly beneficial tool to quantitatively address the competition between normal and leukaemic haematopoiesis in treated CML patients. They derive testable predictions for different experimental settings that are suggested before the clinical implementation of the combination treatment.