Herpes Simplex Virus Antigens Directly Activate NK Cells via TLR2, Thus Facilitating Their Presentation to CD4 T Lymphocytes
The Journal of Immunology, 04/25/2012
Kim M et al. – NK cells stimulated by TLR2–activating HSV Ags can present Ag alone or augment the role of dendritic cells (DCs) in vitro and perhaps in herpetic lesions or draining lymph nodes. In addition to DCs, NK cells should be considered as targets for adjuvants during HSV vaccine development.