Development of gastric cancer in nonatrophic stomach with highly active inflammation identified by serum levels of pepsinogen and Helicobacter pylori antibody together with endoscopic rugal hyperplastic gastritis
International Journal of Cancer, 04/24/2012
Watanabe M et al. – Combining the two serum tests and endoscopic examination for rugal hyperplastic gastritis (RHG) allowed identification of subjects with more active gastritis and higher cancer risk. No cancer development was observed in these high–risk subjects after H. pylori eradication. Subjects with highly active gastritis identified by the two serological tests and endoscopic RHG constitute a group at high risk of cancer development with H. pylori–infected nonatrophic stomach.