Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases Full Text
BMC Immunology,

Licarete E et al. – Using a chimeric protein, the authors developed a new sensitive and specific ELISA to detect collagen specific antibodies. The results show a low prevalence of collagen VII–specific autoantibodies in inflammatory bowel disease, pemphigus and bullous pemphigoid. Furthermore, they show that the autoimmune response against collagen VII is dominated by IgG4 autoantibodies. The new immunoassay should prove a useful tool for clinical and translational research and should improve the routine diagnosis and disease monitoring in diseases associated with collagen VII–specific autoimmunity.

Please login or register to follow this author.
► Click here to access Full Text, PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

    Currently, there are no available articles.

Your Unread Messages in Internal Medicine

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Internal Medicine Articles

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore