Relationships between serum vitamin D levels, neuromuscular and neuropsychological function and falls in older men and women
Osteoporosis International,  Clinical Article

Menant JC et al. – The findings of this study highlight the associations between vitamin D insufficiency and impairments in physiological and neuropsychological function that predispose older people to fall. The significant relationship between vitamin D insufficiency and falls found in the men may relate to the stronger association found between serum 25OHD levels and dynamic balance measures evident in this male population.

Methods

  • 463 community-dwelling people aged 70–90 years underwent an assessment of physiological and neuropsychological performance and structured interviews relating to comorbidity and disability
  • Fall frequency during 12 months follow-up monitored with monthly falls diaries

Results
  • 21% of men and 44% of women were vitamin D insufficient (serum 25OHD?≤?50 nmol/L)
  • Participants with vitamin D insufficiency had weaker upper and lower limb strength, slower simple finger press and choice stepping reaction time, poorer leaning balance and slower gait speed, after controlling for age and body mass index, and, poorer executive function and visuospatial ability, after controlling for age and education. Vitamin D insufficiency significantly increased the rate of falls in men (IRR=1.94, 95% CI=1.19–3.15) but not in women

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Internal Medicine

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Internal Medicine Articles

1 Sweetened carbonated beverage consumption and cancer risk: Meta-analysis and review European Journal of Cancer Prevention, August 1, 2014    Evidence Based Medicine    Review Article

2 Triglycerides and cardiovascular disease The Lancet, August 19, 2014    Evidence Based Medicine    Clinical Article

3 Effects of intensive glycaemic control on ischaemic heart disease: analysis of data from the randomised, controlled ACCORD trial The Lancet, August 5, 2014    Evidence Based Medicine    Clinical Article

4 Global sodium consumption and death from cardiovascular causes New England Journal of Medicine, August 15, 2014    Evidence Based Medicine    Clinical Article

5 Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis BMJ, August 20, 2014    Evidence Based Medicine    Clinical Article

6 A very low carbohydrate, low saturated fat diet for type 2 diabetes management: a randomized trial Diabetes Care, July 31, 2014    Clinical Article

7 Corticosteroid treatment for community-acquired pneumonia - the STEP trial: study protocol for a randomized controlled trial Full Text Trials, July 16, 2014    Free full text    Evidence Based Medicine    Clinical Article

8 Obesity is a risk factor for significant carotid atherosclerosis in patients aged 39 to 55 years Angiology, July 18, 2014    Evidence Based Medicine    Clinical Article

9 Perioperative atrial fibrillation and the long-term risk of ischemic stroke JAMA, August 26, 2014    Evidence Based Medicine    Clinical Article

10 Changes in circulating leptin levels during acute stress and associations with craving in abstinent smokers: A preliminary investigation Psychoneuroendocrinology, June 20, 2014    Clinical Article

11 A randomized trial of epidural glucocorticoid injections for spinal stenosis New England Journal of Medicine, July 7, 2014    Evidence Based Medicine    Clinical Article

12 QTc changes after meal intake: sex differences and correlates Journal of Electrocardiology, August 27, 2014    Clinical Article

13 Being overweight or obese and risk of developing rheumatoid arthritis among women: A prospective cohort study Annals of Rheumatic Diseases, August 25, 2014    Evidence Based Medicine    Clinical Article

14 Statins and physical activity in older men the osteoporotic fractures in men study JAMA Internal Medicine, June 12, 2014    Evidence Based Medicine    Clinical Article

15 Screening pelvic examinations in asymptomatic, average-risk adult women: An evidence report for a clinical practice guideline from the American college of physicians Annals of Internal Medicine, July 2, 2014    Evidence Based Medicine    Clinical Article

16 Relationship between tea consumption and pancreatic cancer risk: A meta-analysis based on prospective cohort studies and case-control studies European Journal of Cancer Prevention, August 1, 2014    Evidence Based Medicine    Clinical Article

17 Risk of dementia among patients with asthma: a nationwide longitudinal study Journal of the American Medical Directors Association, August 1, 2014    Clinical Article

18 Impact of graduated compression stockings on the prevention of post-thrombotic syndrome - results of a randomized controlled trial Phlebology, August 20, 2014    Evidence Based Medicine    Clinical Article

19 Fruit and vegetable consumption and mortality from all causes, cardiovascular disease, and cancer: systematic review and dose-response meta-analysis of prospective cohort studies BMJ, August 1, 2014    Evidence Based Medicine    Review Article    Clinical Article

20 Screening and prostate cancer mortality: Results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up The Lancet, August 8, 2014    Evidence Based Medicine    Clinical Article

Indexed Journals in Internal Medicine: New England Journal of Medicine, The Lancet, Archives of Internal Medicinemore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close