The significance of low PU.1 expression in patients with acute promyelocytic leukemia

Journal of Hematology & Oncology, 05/11/2012

The results showed that PU.1 expression was lower in patients with APL than other acute myeloid leukemia (AML) subtypes and there was also a trend towards increasing PU.1 expression from AML–M0 to AML–M5, with the exception of AML–M3 (APL). These observations suggested that PU.1 expression was reduced by PML–RARalpha in APL patients.

Print Article Summary Cat 2 CME Report