Parenteral amino acid intakes: possible influences of higher intakes on growth and bone status in preterm infants

Journal of Perinatology, 05/03/2012

Scattolin S et al. – Early higher AA intakes improved growth without short–term AA intolerance. Nutritional parameters could influence bone growth. Lower limb length (LLL) was the anthropometric parameter that best correlated to bone status.

Methods

  • Newborns, weighing <1250g, received standard (S) or higher (H) parenteral AA intakes.
  • Anthropometry, biochemistry and quantitative ultrasound (metacarpus bone transmission time (mcBTT), in us) were measured prospectively.

Results

  • A total of 55 patients in group S and 60 in group H were studied.
  • Significantly better growth rate was found in the H group during the study without signs of intolerance.
  • The authors found a significant decrease in mcBTT from birth to 21 days in the H group; nonetheless, mcBTT at 36 weeks of gestational age significantly positively correlated with early AA and energy intakes.
  • A significant positive correlation between mcBTT and lower limb length (LLL) at 21 days was found.

Print Article Summary Cat 2 CME Report