Abnormal epidermal barrier in the pathogenesis of psoriasis

Clinics in Dermatology, 05/02/2012

Accumulating data indicate that there is an association of psoriasis and mutations of genes within the epidermal differentiation complex, which are crucial for the development, maturation, cornification, cross–linking, and terminal differentiation of the epidermis, called psoriasis susceptibility locus 4.

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