Induction Chemotherapy and Dose Intensification of the Radiation Boost in Locally Advanced Anal Canal Carcinoma

Journal of Clinical Oncology, 04/25/2012

Using colostomy–free survival (CFS). as the main end point, the authors did not find an advantage for either induction chemotherapy (ICT) or HD radiation boost in locally advanced anal canal carcinoma (LAACC). Nevertheless, the results of the most treatment–intense arm B should prompt the design of further intensification studies.

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