Incidence and Prevalence of Unrecognized Myocardial Infarction in People With Diabetes Mellitus: A substudy of the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study
Diabetes Care, 05/13/2011MacDonald MR et al.
Although the prevalence and incidence of myocardial infarction was low, unrecognized Q–wave myocardial infarctions made up a substantial proportion of all events.
The authors performed a retrospective analysis of the electrocardiograms (ECGs) recorded at baseline and after 2 years for the first 1,004 type 2 diabetic individuals to be randomized in the Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycemia in Diabetes (RECORD) study.
ECGs suitable for analysis were obtained from 669 participants.
The prevalence of unrecognized Q–wave myocardial infarction at baseline was 1.9% (n = 13).
The incidence of unrecognized Q–wave myocardial infarction at the end of 2 years of follow–up was 1.5/1,000–person–years (n = 2).
One–third (13 of 39) of prevalent and one–quarter (2 of 8) of incident myocardial infarctions were unrecognized.
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