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Relation Between Mean Platelet Volume and Severity of Atherosclerosis in Patients With Acute Coronary Syndromes

Murat SN et al. – It is possible that mean platelet volume (MPV) can be a helpful marker in patients with coronary artery disease (CAD) for the severity of coronary atherosclerosis.

  • The authors evaluated the relationship between MPV and severity of CAD in patients with ACS.
  • A total of 395 patients with ACS were included.
  • Severity of CAD was assessed with the Gensini and Syntax scores.

  • High levels of MPV were associated with the Gensini and Syntax scores, number of diseased vessels (>50%), number of critical lesions (>50% and >70%), and noncritical lesions.
  • After multivariate analysis, high levels of MPV were independent predictors of multivessel CAD together with age.


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