1Effect of sedative premedication on patient experience after general anesthesia: a randomized clinical trialJAMA  Clinical Article  Evidence Based Medicine
2Irritable bowel syndrome: a clinical reviewJAMA  Clinical Article  Evidence Based Medicine
3The movement of multidrug-resistant tuberculosis across borders in East Africa needs a regional and global solutionPLoS Medicine  Full Text  Evidence Based Medicine
4Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysisPLoS Medicine  Full Text  Clinical Article  Evidence Based Medicine
5Humanitarian access to unapproved interventions in public health emergencies of international concernPLoS Medicine  Full Text  Evidence Based Medicine
6Is neuroplasticity in the central nervous system the missing link to our understanding of chronic musculoskeletal disorders?BMC Musculoskeletal Disorders  Full Text
7An analysis of calibration and discrimination among multiple cardiovascular risk scores in a modern multiethnic cohortAnnals of Internal Medicine  Evidence Based Medicine
8Relapse in psoriasis with two different tapering regimens of methotrexate: A randomized open-label controlled studyIndian Journal of Dermatology, Venereology and Leprology  Full Text  Clinical Article
9Time-updated systolic blood pressure and the progression of chronic kidney disease: a cohort studyAnnals of Internal Medicine  Clinical Article  Evidence Based Medicine
10Pancreatic adipose tissue infiltration, parenchymal steatosis and beta cell function in humansDiabetologia - Clinical and Experimental Diabetes and Metabolism  Clinical Article
1Often-ignored glucose value in routine blood tests correlates with risk of type 2 diabetesUT Southwestern Medical Center
2Gut bacteria may contribute to diabetes in black malesUniversity of Illinois at Chicago Health News
3New understanding of stroke damage may aid recoveryWashington University School of Medicine in St. Louis News
4Gut bacteria may decrease weight loss from bariatric surgeryCedars-Sinai
5Gut bacteria may decrease weight loss from bariatric surgery: New study by Cedars-Sinai investigator presented at ENDO 2015 this weekCedars-Sinai
6Researchers discover protein's pivotal role in heart failureUC San Diego Health System
7Adults only really catch flu about twice a decade, suggests studyImperial College London Health News
8Semi-veggie diet effectively lowers heart disease, stroke riskAmerican Heart Association News
9Understanding how the stomach responds to injury could help target therapy against gastric damageAmerican Gastroenterological Association News
10University of Florida researchers find source of some middle-age memory problemsUF Health

Show Me:

Soluble TNF receptor II increased in MS patients

As reported in the Journal of Neuroimmunology, soluble tumor necrosis factor receptor II levels are increased in patients with untreated multiple sclerosis (n-161) compared to healthy controls (n=46), and the levels increased over a 2-year follow-up, but were not associated with the severity of disability.

Mean platelet volume predicts silent cerebral infarction

As reported in the Internal Medicine Journal, the mean platelet volume is increased in patients with a silent cerebral infarction than in those without (10.4 vs. 9.2 fL). The OR for silent cerebral infarction was 7.822 in patients in the highest mean platelet volume quartile compared to the lowest quartile.

Relationship benefit in women with IHD

As reported in Clinical Infectious Diseases, HIV-infected patients are at increased risk for non-Hodgkin‘s lymphoma (NHL). Of 6036 patients with 21607 person-years of follow-up, there were 37 incident cases of NHL. Compared to patients with ≤ 50 copies/mL, patients with 51-500 and > 500 copies/mL had HRs of 1.66 and 2.39 for NHL, respectively.

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Clinical Pearls

Clinical Pearl from Smartest DocDer bivalente HPV-Impfstoff kann die HPV-bezogene Morbidität und Mortalität um bis zu 8,4 Jahre verringern.

Clinical Pearl from Smartest DocCOX-2 inhibitors do not cross-react with aspirin.

Clinical Pearl from Smartest DocBath salts have dangerous health effects and a risk of addiction.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List