Internal Medicine News Articles

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Our team of medical editors read over 2,000 medical journals daily so you can stay current on today's latest Internal Medicine news in medical research, review articles and biomedical science. They sort, rank and summarize every article that will impact your daily practice. They even mark which articles are available in free full text, which are clinical or evidence-based, and which have Exclusive Author Commentary from the people who actually performed the clinical research.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Mortality in rheumatoid arthritis: the impact of disease activity, treatment with glucocorticoids, TNF{alpha} inhibitors and rituximab Annals of Rheumatic Diseases, January 27, 2015    Evidence Based Medicine    Clinical Article

2 Trends in the incidence of hip fracture in Gran Canaria, Canary Islands, Spain: 2007-2011 versus 1989-1993 Osteoporosis International, January 27, 2015    Evidence Based Medicine    Clinical Article

3 Long-term safety and efficacy of single-tablet combinations of solifenacin and tamsulosin oral controlled absorption system in men with storage and voiding lower urinary tract symptoms: Results from the neptune study and neptune II open-label extension Full Text European Urology, January 27, 2015    Clinical Article

4 Discontinuation of adalimumab after achieving remission in patients with established rheumatoid arthritis: 1-year outcome of the HONOR study Annals of Rheumatic Diseases, January 27, 2015    Evidence Based Medicine    Clinical Article

5 More extensive pelvic lymph node dissection improves survival in patients with node-positive prostate cancer Full Text European Urology, January 27, 2015    Clinical Article

6 Can vitamin D metabolite measurements facilitate a “treat-to-target” paradigm to guide vitamin D supplementation? Osteoporosis International, January 27, 2015    Evidence Based Medicine    Clinical Article

7 Comparison of tocilizumab as monotherapy or with add-on disease-modifying antirheumatic drugs in patients with rheumatoid arthritis and inadequate responses to previous treatments: an open-label study close to clinical practice Clinical Rheumatology, January 27, 2015    Evidence Based Medicine    Clinical Article

8 Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins Annals of Rheumatic Diseases, January 27, 2015    Evidence Based Medicine    Clinical Article

9 Reasons for failure to receive pneumococcal and influenza vaccinations among immunosuppressed patients with systemic lupus erythematosus Seminars in Arthritis and Rheumatism, January 27, 2015    Evidence Based Medicine    Clinical Article

10 Incidence of herpes zoster in HIV-infected adults in the combined antiretroviral therapy era: results from the FHDH-ANRS CO4 cohort Clinical Infectious Diseases, January 27, 2015    Clinical Article

11 Multicenter assessment of neoadjuvant chemotherapy for muscle-invasive bladder cancer Full Text European Urology, January 27, 2015    Clinical Article

12 Treatment initiation factors and cognitive outcome in youth with perinatally acquired HIV infection HIV Medicine, January 27, 2015    Clinical Article

13 A short-term risk-benefit analysis of occasional and regular use of low-dose aspirin in primary prevention of vascular diseases: a nationwide population-based study BMJ Open, January 27, 2015    Clinical Article

14 Diabetes as a risk factor for medication-related osteonecrosis of the jaw Journal of Dental Research , January 27, 2015    Review Article    Clinical Article

15 Nomograms to predict survival and the risk for developing local or distant recurrence in patients with rectal cancer treated with optional short-term radiotherapy Annals of Oncology, January 27, 2015    Clinical Article

16 Effect of protein overfeeding on energy expenditure measured in a metabolic chamber American Journal of Clinical Nutrition, January 27, 2015    Clinical Article

17 Lathosterol-to-cholesterol ratio in serum predicts cholesterol-lowering response to plant sterol consumption in a dual-center, randomized, single-blind placebo-controlled trial American Journal of Clinical Nutrition, January 27, 2015    Clinical Article

18 Satiation attenuates BOLD activity in brain regions involved in reward and increases activity in dorsolateral prefrontal cortex: an fMRI study in healthy volunteers American Journal of Clinical Nutrition, January 27, 2015    Clinical Article

19 Physical activity and all-cause mortality across levels of overall and abdominal adiposity in European men and women: the European Prospective Investigation into Cancer and Nutrition Study (EPIC) American Journal of Clinical Nutrition, January 27, 2015    Clinical Article

20 Prenatal exposure to methyl mercury from fish consumption and polyunsaturated fatty acids: associations with child development at 20 mo of age in an observational study in the Republic of Seychelles American Journal of Clinical Nutrition, January 27, 2015    Clinical Article

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Highlights in Internal Medicine

Relationship benefit in women with IHD

As reported in Clinical Infectious Diseases, HIV-infected patients are at increased risk for non-Hodgkin‘s lymphoma (NHL). Of 6036 patients with 21607 person-years of follow-up, there were 37 incident cases of NHL. Compared to patients with ≤ 50 copies/mL, patients with 51-500 and > 500 copies/mL had HRs of 1.66 and 2.39 for NHL, respectively.

Mean platelet volume predicts silent cerebral infarction

As reported in the Internal Medicine Journal, the mean platelet volume is increased in patients with a silent cerebral infarction than in those without (10.4 vs. 9.2 fL). The OR for silent cerebral infarction was 7.822 in patients in the highest mean platelet volume quartile compared to the lowest quartile.

Muscle strength in adolescence decreases CVD risk

As reported in BMC Medicine, adolescents (n=38588) with the highest tertile of muscle strength had a decreased risk of CVD (HR=0.88) compared to adolescents with the lowest tertile of muscle strength after 42 y of follow-up. Of note, low muscle strength in adolescence by itself had no effect on CVD risk in middle age (HR=0.99). In contrast, high muscle strength in adolescence significantly decreased the risk of CVD in middle age (HR=1.31).

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