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1 Acupuncture for chronic knee pain: a randomized clinical trial JAMA, October 1, 2014    Evidence Based Medicine    Clinical Article

2 Women's experiences of low back pain during pregnancy Journal of Back and Musculoskeletal Rehabilitation, October 1, 2014    Evidence Based Medicine    Clinical Article

3 Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: A retrospective cohort study The Lancet Infectious Diseases, October 1, 2014    Clinical Article

4 Effect of hypoglycemia on brain structure in people with type 2 diabetes: epidemiological analysis of the ACCORD-MIND MRI Trial Diabetes Care, October 1, 2014    Review Article

5 Early management of patients with acute heart failure: state of the art and future directions. a consensus document from the society for academic emergency medicine/heart failure society of America acute heart failure working group Journal of Cardiac Failure, October 1, 2014    Clinical Article

6 Estimating the treatment cascade of chronic hepatitis B and C in Greece using a telephone survey Journal of Viral Hepatitis, October 1, 2014    Clinical Article

7 Effects of polymorphisms in interferon λ 3 (interleukin 28b) on sustained virologic response to therapy in patients with chronic hepatitis D virus infection Clinical Gastroenterology and Hepatology , October 1, 2014    Clinical Article

8 Significantly higher rates of gastrointestinal bleeding and thromboembolic events with left ventricular assist devices Clinical Gastroenterology and Hepatology , October 1, 2014    Clinical Article

9 Effects of topical steroids on tight junction proteins and spongiosis in esophageal epithelia of patients with eosinophilic esophagitis Clinical Gastroenterology and Hepatology , October 1, 2014    Clinical Article

10 Disc extrusions and bulges in nonspecific low back pain and sciatica: Exploratory randomised controlled trial comparing yoga therapy and normal medical treatment Journal of Back and Musculoskeletal Rehabilitation, October 1, 2014    Evidence Based Medicine

11 Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis Clinical Gastroenterology and Hepatology , October 1, 2014    Clinical Article

12 Safety of coronary angiography and percutaneous coronary intervention via the radial versus femoral route in patients on uninterrupted oral anticoagulation with warfarin American Heart Journal, October 1, 2014    Clinical Article

13 The effect of indapamide versus hydrochlorothiazide on ventricular and arterial function in patients with hypertension and diabetes: Results of a randomized trial American Heart Journal, October 1, 2014    Clinical Article

14 Electrocardiographic abnormalities and coronary artery calcium for coronary heart disease prediction and reclassification: The Multi-Ethnic Study of Atherosclerosis (MESA) American Heart Journal, October 1, 2014    Clinical Article

15 Cardioprotective role of ischemic postconditioning in acute myocardial infarction: A systematic review and meta-analysis American Heart Journal, October 1, 2014    Evidence Based Medicine    Review Article    Clinical Article

16 Comparative analysis of monoclonal antibodies against prostate-specific membrane antigen (PSMA) The Prostate, October 1, 2014    Clinical Article

17 Clinical outcomes in patients with isolated left ventricular noncompaction and heart failure Journal of Cardiac Failure, October 1, 2014    Clinical Article

18 Sleep duration affects risk for ulcerative colitis: a prospective cohort study Clinical Gastroenterology and Hepatology , October 1, 2014    Clinical Article

19 Acute heart failure with and without concomitant acute coronary syndromes: patient characteristics, management, and survival Journal of Cardiac Failure, October 1, 2014    Clinical Article

20 Cardiac sarcoidosis with ventricular tachycardia and echocardiography Journal of Cardiac Failure, October 1, 2014    Clinical Article

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Highlights in Internal Medicine

Muscle strength in adolescence decreases CVD risk

As reported in BMC Medicine, adolescents (n=38588) with the highest tertile of muscle strength had a decreased risk of CVD (HR=0.88) compared to adolescents with the lowest tertile of muscle strength after 42 y of follow-up. Of note, low muscle strength in adolescence by itself had no effect on CVD risk in middle age (HR=0.99). In contrast, high muscle strength in adolescence significantly decreased the risk of CVD in middle age (HR=1.31).

Relationship benefit in women with IHD

As reported in Clinical Infectious Diseases, HIV-infected patients are at increased risk for non-Hodgkin‘s lymphoma (NHL). Of 6036 patients with 21607 person-years of follow-up, there were 37 incident cases of NHL. Compared to patients with ≤ 50 copies/mL, patients with 51-500 and > 500 copies/mL had HRs of 1.66 and 2.39 for NHL, respectively.

Sleep duration linked to lung cancer risk

As reported in BMC Public Health, men (age range, 42-60 years) who slept < 7 h/night or > 8 h/night are at increased risk for lung cancer. Specifically, amongst current smokers, the HR for lung cancer in men who slept < 6.5 h/night or > 8 h/night was 2.23 and 2.09, respectively. It is thought that melatonin excretion and/or low-grade inflammation account for this observation.


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