Internal Medicine News Articles

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial The Lancet, July 28, 2014    Evidence Based Medicine    Clinical Article

2 Clinical and radiological dissociation of anti-TNF plus methotrexate treatment in early rheumatoid arthritis in routine care: Results from the ABRAB study Full Text BMC Musculoskeletal Disorders, July 28, 2014    Evidence Based Medicine    Clinical Article

3 Laboratory aspirin resistance reversibility in diabetic patients: a pilot study using different pharmaceutical formulations Cardiovascular Drugs and Therapy, July 28, 2014    Clinical Article

4 Homelike living for elderly people: A needs-based selection of technological solutions Home Health Care Management & Practice, July 28, 2014

5 Combination antiretroviral therapy helps treat hepatitis C in HIV patients University of Cincinnati Academic Health Center, July 28, 2014

6 AIDS-free generation is aim of new guidelines for clinicians UW Medicine, July 28, 2014    Clinical Guideline

7 Study: Protein therapy successful in treating injured lung cells The Ohio State University Wexner Medical Center, July 28, 2014

8 Increased serum free light chains precede the presentation of immunoglobulin light chain amyloidosis Journal of Clinical Oncology, July 28, 2014    Clinical Article

9 African Americans with cancer pain are more likely to receive an analgesic with toxic metabolite despite clinical risks: A mediation analysis study Journal of Clinical Oncology, July 28, 2014    Clinical Article

10 Effect of routine assessment of specific psychosocial problems on personalized communication, counselors’ awareness, and distress levels in cancer genetic counseling practice: a randomized controlled trial Journal of Clinical Oncology, July 28, 2014    Clinical Article

11 Phase ii randomized trial comparing sequential first-line everolimus and second-line sunitinib versus first-line sunitinib and second-line everolimus in patients with metastatic renal cell carcinoma Journal of Clinical Oncology, July 28, 2014    Clinical Article

12 Front-line transplantation program with lenalidomide, bortezomib, and dexamethasone combination as induction and consolidation followed by lenalidomide maintenance in patients with multiple myeloma: A phase II study by the intergroupe francophone du Myélome Journal of Clinical Oncology, July 28, 2014    Clinical Article

13 Association between antipsychotic use and risk of acute myocardial infarction Circulation, July 28, 2014    Clinical Article

14 Serotype-specific effectiveness and correlates of protection for the 13-valent pneumococcal conjugate vaccine: A postlicensure indirect cohort study The Lancet Infectious Diseases, July 28, 2014    Clinical Article

15 Diabetes, antidiabetic medications and pancreatic cancer risk: an analysis from the international pancreatic cancer case-control consortium Annals of Oncology, July 28, 2014    Clinical Article

16 Reduced cerebral grey matter and altered white matter in boys with Duchenne muscular dystrophy Annals of Neurology , July 28, 2014    Clinical Article

17 Recurrence and mortality among patients hospitalized for acute lower gastrointestinal bleeding Clinical Gastroenterology and Hepatology , July 28, 2014    Clinical Article

18 Incidence of malignancies in diagnosed celiac patients: a population-based estimate The American Journal of Gastroenterology, July 28, 2014    Clinical Article

19 Plasmakinetic enucleation of the prostate compared with open prostatectomy for prostates larger than 100 grams: A randomized noninferiority controlled trial with long-term results at 6 years Full Text European Urology, July 28, 2014    Clinical Article

20 Visit-to-visit variability in blood pressure and kidney and cardiovascular outcomes in patients with type 2 diabetes and nephropathy: A post hoc analysis from the RENAAL Study and the Irbesartan Diabetic Nephropathy Trial American Journal of Kidney Diseases, July 28, 2014    Clinical Article

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Clinical Pearls in Internal Medicine

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Highlights in Internal Medicine

Muscle strength in adolescence decreases CVD risk

As reported in BMC Medicine, adolescents (n=38588) with the highest tertile of muscle strength had a decreased risk of CVD (HR=0.88) compared to adolescents with the lowest tertile of muscle strength after 42 y of follow-up. Of note, low muscle strength in adolescence by itself had no effect on CVD risk in middle age (HR=0.99). In contrast, high muscle strength in adolescence significantly decreased the risk of CVD in middle age (HR=1.31).

Soluble TNF receptor II increased in MS patients

As reported in the Journal of Neuroimmunology, soluble tumor necrosis factor receptor II levels are increased in patients with untreated multiple sclerosis (n-161) compared to healthy controls (n=46), and the levels increased over a 2-year follow-up, but were not associated with the severity of disability.

Sleep duration linked to lung cancer risk

As reported in BMC Public Health, men (age range, 42-60 years) who slept < 7 h/night or > 8 h/night are at increased risk for lung cancer. Specifically, amongst current smokers, the HR for lung cancer in men who slept < 6.5 h/night or > 8 h/night was 2.23 and 2.09, respectively. It is thought that melatonin excretion and/or low-grade inflammation account for this observation.

Other Topics in Internal Medicine

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