Toll-Like Receptor and Hepatitis B Virus Clearance in Chronic Infected Patients: A Long-Term Prospective Cohort Study in Taiwan
The Journal of Infectious Diseases, 06/29/2012
Wu JF et al. – TLR5 rs5744174 (p.Phe616Leu) and TLR9 rs5743836 promoter area polymorphism associated with earlier spontaneous HBeAg seroconversion. TLR4 rs4986790 (p.Asp299Gly) associated with HBsAg seroclearance/seroconversion in chronic HBV patients. TLR5 rs5744174 (p.Phe616Leu) associated with higher interferon–γ production in chronic HBV infected patients.