Renal safety of tenofovir containing antiretroviral regimen in a Singapore cohort
AIDS Research and Therapy, 06/25/2012
Chua AC et al. – While authors noted renal toxicity to be rare and transient among the cohort receiving TDF as part of their ARV regimen, these results reflect the short term renal effects of TDF given that ARV treatment is lifelong. Given that laboratory monitoring may be difficult to implement in many situations, future prospective studies looking into an evidence based algorithm for less frequent renal function monitoring than current guideline recommendations may be helpful.