Diagnostic performance of line-immunoassay based algorithms for incident HIV-1 infection

BMC Infectious Diseases, 04/13/2012

The method can be used for comparing IIR in annual cohorts of HIV notifications. The use of several different algorithms in combination, each with its own sensitivity and specificity to detect incident infection, is advisable as this reduces the impact of individual imperfections stemming primarily from relatively low sensitivities and sampling bias.

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