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A comparative study of the typhidot (Dot-EIA) and Widal tests in blood culture positive cases of typhoid fever
Tropical Doctor, 09/09/2011
Khoharo HK – The typhidot test was positive in 74 cases, with a sensitivity, specificity and positive predictive value of 96%, 89.5%, and 95%, respectively, compared to the Widal test which was positive in 56 cases with a sensitivity, specificity, and positive predictive value of 72%, 87%, and 87%, respectively. In the control group, seven cases tested positive for the Widal test and two for the typhidot, yielding the sensitivity and specificity for the Widal test and the typhidot test of 63% and 83%, and 85% and 97%, respectively. The authors conclude that the Dot–EIA (enzyme immunoassay; typhidot) is a more sensitive and specific test which is easy to perform and more reliable compared to the Widal test and that it is useful in early therapy.
