New approaches to the treatment of giardiasis
Current Opinion in Infectious Diseases, 09/07/2011
Tejman–Yarden N et al. – Derivatives of benzimidazole, the structural core of the effective antigiardial albendazole, are also exhibiting promising new activities. Beyond lead modifications, several new classes of antigiardial drug candidates have recently been identified by high-throughput screening of large compound libraries, and first efforts have been reported on the development of drugs tailored to known molecular targets in Giardia. Many challenges are still to be expected before clinical utility of new antigiardial drugs can be established.






