Factors associated with mortality in patients with drug-susceptible pulmonary tuberculosis Full Text
BMC Infectious Diseases, 01/04/2011
Nahid P et al. – Tuberculosis is a leading cause of death worldwide, yet the determinants of death are not well understood. The authors sought to determine risk factors for mortality during treatment of drug–susceptible pulmonary tuberculosis under program settings. In addition to advanced age, HIV and characteristics of advanced tuberculosis, experiencing an interruption in anti–tuberculosis therapy, primarily due to non–adherence, was also independently associated with increased risk of death. Improving adherence early during treatment for tuberculosis may both improve tuberculosis outcomes as well as decrease mortality.