The Neutrophil Respiratory Burst and Bacterial Digestion in Crohn's Disease
Digestive Diseases and Sciences, 10/15/2010
Hayee BH et al. – The significant reduction in neutrophil respiratory burst in Crohn's Disease does not appear to result in defective bacterial digestion and is therefore unlikely play a major role in pathogenesis. Three patients in this cohort of patients with presumed idiopathic Crohn's Disease were found to have a profound defect of the neutrophil respiratory burst. A high index of suspicion for such patients is prudent, as their prognosis can be improved by altering or augmenting the conventional treatment regimens employed for Crohn's Disease.