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Infectious Disease - Basic Science/Genetics News & Articles

MDLinx Infectious Disease – your first and best resource for the top literature, summarized and sorted to keep you current in just five minutes or less a day! Here, find exclusive content like highlighted articles you can’t miss from our physician editor D. Scott Cunningham, MD, PhD, and clinical pearls you can apply to your day to day, taken from recent Smartest Doc daily quiz competitions and Physician Reviews.

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Articles

Latest (2) Full Text Articles (241)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

1 The interactions and essential effects of intrinsic insulin-like growth factor-i on leishmania (leishmania) major growth within macrophages Parasite Immunology, May 22, 2013    Review Article

2 Mir-146a facilitates replication of dengue virus by dampening interferon induction by targeting traf6 Journal of Infection, May 22, 2013    Review Article

Prior Articles

3 Polymorphism of the parasite lactate dehydrogenase gene from Plasmodium vivax Korean isolates Full Text Malaria Journal, May 21, 2013    Review Article

4 Enzymatic and molecular characterisation of leucine aminopeptidase of Burkholderia pseudomallei Full Text BMC Microbiology, May 21, 2013    Review Article

5 Comparison of the effects of extracts from three vitex plant species on anopheles gambiae s.s. (diptera: Culicidae) larvae Acta Tropica, May 21, 2013    Review Article

6 Morphological aspects of Angiostrongylus costaricensis by light and scanning electron microscopy Acta Tropica, May 21, 2013    Review Article

7 The C-type Lectin Receptors Dectin-1, MR, and SIGNR3 Contribute Both Positively and Negatively to the Macrophage Response to Leishmania infantum Immunity, May 21, 2013    Review Article

8 Identification of 11 new exoproteins in Corynebacterium pseudotuberculosis by comparative analysis of the exoproteome Microbial Pathogenesis, May 21, 2013    Review Article

9 Relationship between MIF-173 G/C polymorphism and susceptibility to chronic hepatitis B and HBV-induced liver cirrhosis Cellular Immunology, May 20, 2013    Clinical Article

10 Differential Activation of Diverse Glutathione Transferases of Clonorchis sinensis in Response to the Host Bile and Oxidative Stressors Full Text PLoS Neglected Tropical Diseases, May 17, 2013

11 Fine Analysis of Genetic Diversity of the tpr Gene Family among Treponemal Species, Subspecies and Strains Full Text PLoS Neglected Tropical Diseases, May 17, 2013    Review Article

12 DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia Full Text PLoS Neglected Tropical Diseases, May 17, 2013    Review Article

13 CD4 T Cell Responses in Latent and Chronic Viral Infections Frontiers in Immunology, May 17, 2013    Review Article

14 Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore PLOS ONE, May 17, 2013    Review Article

15 Adaptive Mutations and Replacements of Virulence Traits in the Escherichia coli O104:H4 Outbreak Population PLOS ONE, May 17, 2013    Review Article

16 The Receptor Attachment Function of Measles Virus Hemagglutinin Can Be Replaced with an Autonomous Protein That Binds Her2/neu While Maintaining Its Fusion-Helper Function Journal of Virology, May 17, 2013    Review Article

17 TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium Journal of Virology, May 17, 2013    Review Article

18 Identification and Characterization of Genetically Divergent Members of the Newly Established Family Mesoniviridae Journal of Virology, May 17, 2013    Review Article

19 HIV-1 Gag Associates with Specific Uropod-Directed Microdomains in a Manner Dependent on Its MA Highly Basic Region Journal of Virology, May 17, 2013    Review Article

20 Role of E1B55K in E4orf6/E1B55K E3 Ligase Complexes Formed by Different Human Adenovirus Serotypes Journal of Virology, May 17, 2013    Review Article

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Clinical Pearls in Infectious Disease

Highlights in Infectious Disease

Predicting decompensation during severe acute exacerbation of hepatitis B

In a study involving 37 patients with chronic hepatitis B infections, a serum bilirubin level > 5 mg/dL was predictive of progression to hepatic failure and liver-related death.

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Three risk factors for mortality in the elderly with pneumonia identified

In a study involving 1607 patients > 65 years of age with community- or healthcare-acquired pneumonia, pre-morbid ambulation impairment (OR=2.61), hospitalization within 30 days of acquiring pneumonia (OR=1.93), and absence of cough and purulent sputum (OR=1.47) were shown to be associated with a significant increase in 30-day mortality.

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Tobacco and alcohol abuse in HPV-positive patients increase risk of esophageal squamous cell carcinoma

In a retrospective study involving 225 patients with esophageal squamous cell carcinoma (ESCC) and 224 matched controls, it was shown that patients who were HPV-positive and smoked cigarettes or smoked cigarettes plus consumed alcohol were at increased risk for ESCC than patients who were HPV-negative (OR = 2.22 and 10.31, respectively).

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