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Infectious Disease News & Articles

MDLinx Infectious Disease – your first and best resource for the top literature, summarized and sorted to keep you current in just five minutes or less a day! Here, find exclusive content like highlighted articles you can’t miss from our physician editor D. Scott Cunningham, MD, PhD, and clinical pearls you can apply to your day to day, taken from recent Smartest Doc daily quiz competitions and Physician Reviews.

Your Unread Messages in Infectious Disease

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Articles

Latest (88) Full Text Articles (1945)
Ranked, sorted, and summarized by MDLinx editors from the latest literature
Topics:

41 Complement activation in pediatric patients with recurrent acute otitis media International Journal of Pediatric Otorhinolaryngology , May 17, 2013    Clinical Article

42 Biotechnology advances: A perspective on the diagnosis and research of Rabies Virus Biologicals, May 17, 2013    Review Article

43 Audit of the practice of sputum smear examination for patients with suspected pulmonary tuberculosis in Fiji Transactions of the Royal Society of Tropical Medicine and Hygiene, May 17, 2013    Clinical Article

44 CD4 T Cell Responses in Latent and Chronic Viral Infections Frontiers in Immunology, May 17, 2013    Review Article

45 Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore PLOS ONE, May 17, 2013    Review Article

46 Adaptive Mutations and Replacements of Virulence Traits in the Escherichia coli O104:H4 Outbreak Population PLOS ONE, May 17, 2013    Review Article

47 The Receptor Attachment Function of Measles Virus Hemagglutinin Can Be Replaced with an Autonomous Protein That Binds Her2/neu While Maintaining Its Fusion-Helper Function Journal of Virology, May 17, 2013    Review Article

48 TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium Journal of Virology, May 17, 2013    Review Article

49 Identification and Characterization of Genetically Divergent Members of the Newly Established Family Mesoniviridae Journal of Virology, May 17, 2013    Review Article

50 HIV-1 Gag Associates with Specific Uropod-Directed Microdomains in a Manner Dependent on Its MA Highly Basic Region Journal of Virology, May 17, 2013    Review Article

51 Role of E1B55K in E4orf6/E1B55K E3 Ligase Complexes Formed by Different Human Adenovirus Serotypes Journal of Virology, May 17, 2013    Review Article

52 The Transcriptome of the Baculovirus Autographa californica Multiple Nucleopolyhedrovirus in Trichoplusia ni Cells Journal of Virology, May 17, 2013    Review Article

53 Isolation and Characterization of Current Human Coronavirus Strains in Primary Human Epithelial Cell Cultures Reveal Differences in Target Cell Tropism Journal of Virology, May 17, 2013    Review Article

54 The Transmembrane Domain of the Adenovirus E3/19K Protein Acts as an Endoplasmic Reticulum Retention Signal and Contributes to Intracellular Sequestration of Major Histocompatibility Complex Class I Molecules Journal of Virology, May 17, 2013    Review Article

55 Tyrosine 132 Phosphorylation of Influenza A Virus M1 Protein Is Crucial for Virus Replication by Controlling the Nuclear Import of M1 Journal of Virology, May 17, 2013    Review Article

56 Recombination within the Pandemic Norovirus GII.4 Lineage Journal of Virology, May 17, 2013    Review Article

57 Deciphering the Mechanism of Defective Interfering RNA (DI RNA) Biogenesis Reveals That a Viral Protein and the DI RNA Act Antagonistically in Virus Infection Journal of Virology, May 17, 2013    Review Article

58 Generation of Genetically Stable Recombinant Rotaviruses Containing Novel Genome Rearrangements and Heterologous Sequences by Reverse Genetics Journal of Virology, May 17, 2013    Review Article

59 Structure-Function Analysis of Severe Acute Respiratory Syndrome Coronavirus RNA Cap Guanine-N7-Methyltransferase Journal of Virology, May 17, 2013    Review Article

60 The ULb' Region of the Human Cytomegalovirus Genome Confers an Increased Requirement for the Viral Protein Kinase UL97 Journal of Virology, May 17, 2013    Review Article

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Clinical Pearls in Infectious Disease

Highlights in Infectious Disease

Predicting decompensation during severe acute exacerbation of hepatitis B

In a study involving 37 patients with chronic hepatitis B infections, a serum bilirubin level > 5 mg/dL was predictive of progression to hepatic failure and liver-related death.

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Three risk factors for mortality in the elderly with pneumonia identified

In a study involving 1607 patients > 65 years of age with community- or healthcare-acquired pneumonia, pre-morbid ambulation impairment (OR=2.61), hospitalization within 30 days of acquiring pneumonia (OR=1.93), and absence of cough and purulent sputum (OR=1.47) were shown to be associated with a significant increase in 30-day mortality.

Read the article summary

Tobacco and alcohol abuse in HPV-positive patients increase risk of esophageal squamous cell carcinoma

In a retrospective study involving 225 patients with esophageal squamous cell carcinoma (ESCC) and 224 matched controls, it was shown that patients who were HPV-positive and smoked cigarettes or smoked cigarettes plus consumed alcohol were at increased risk for ESCC than patients who were HPV-negative (OR = 2.22 and 10.31, respectively).

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Most Popular Infectious Disease Articles

Last month's top read Top Articles of 2012

1 Early Use of Daptomycin Versus Vancomycin for Methicillin-Resistant Staphylococcus aureus Bacteremia With Vancomycin Minimum Inhibitory Concentration >1 mg/L: A Matched Cohort Study Clinical Infectious Diseases, April 1, 2013

2 Herpes Zoster Vaccine Effectiveness against Incident Herpes Zoster and Post-herpetic Neuralgia in an Older US Population: A Cohort Study PLoS Medicine, April 12, 2013    Free full text

3 Infective Endocarditis New England Journal of Medicine, April 12, 2013

4 Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections Cochrane Reviews, March 29, 2013    Review Article

5 Discontinuation of Contact Precautions for Methicillin-Resistant Staphylococcus aureus (MRSA): A Randomized Controlled Trial Comparing Passive and Active Screening with Culture and Polymerase Chain Reaction Clinical Infectious Diseases, April 11, 2013

6 Entry Inhibitors and their use in the Treatment of HIV-1 Infection Antiviral Research , April 2, 2013

7 Measles transmission during air travel, United States, December 1, 2008-December 31, 2011 Travel Medicine and Infectious Disease , April 5, 2013

8 Durable Efficacy and Safety of Raltegravir Versus Efavirenz When Combined With Tenofovir/Emtricitabine in Treatment-Naive HIV-1–Infected Patients: Final 5-Year Results From STARTMRK Journal of Acquired Immune Deficiency Syndromes, April 16, 2013

9 Clinical Trial: Comparative Effectiveness of Cephalexin Plus Trimethoprim-Sulfamethoxazole Versus Cephalexin Alone for Treatment of Uncomplicated Cellulitis: A Randomized Controlled Trial Clinical Infectious Diseases, April 3, 2013

10 Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort Multiple Sclerosis Journal, April 1, 2013

11 Stop Antibiotics on guidance of Procalcitonin Study (SAPS): a randomised prospective multicenter investigator-initiated trial to analyse whether daily measurements of procalcitonin versus a standard-of-care approach can safely shorten antibiotic duration in intensive care unit patients - calculated sample size: 1816 patients BMC Infectious Diseases, April 19, 2013    Free full text

12 Current assays for HIV-1 diagnostics and antiretroviral therapy monitoring: challenges and possibilities Future Virology, April 15, 2013    Review Article

13 A Pill for HIV Prevention: Deja Vu All Over Again Clinical Infectious Diseases, March 28, 2013

14 Prevalence and predictors of hepatitis B virus co-infection in a United States cohort of hepatitis C virus-infected patients Hepatology, March 19, 2013

15 Linezolid versus vancomycin for meticillin-resistant Staphylococcus aureus infection: a meta-analysis of randomised controlled trials International Journal of Antimicrobial Agents, April 23, 2013    Evidence Based Medicine

16 Marital status and HIV/AIDS mortality: evidence from the US National Longitudinal Mortality Study International Journal of Infectious Diseases, April 9, 2013

17 De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock Cochrane Reviews, April 11, 2013    Review Article

18 Contribution of genetic background, traditional risk factors and HIV-related factors to coronary artery disease events in HIV-positive persons Clinical Infectious Diseases, April 1, 2013

19 Cobicistat: A New Boost for the Treatment of Human Immunodeficiency Virus Infection Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, March 13, 2013

20 A Conceptual Framework for Understanding Chronic Pain in Patients with HIV Pain Practice, April 5, 2013

Indexed Journals in Infectious Disease: Journal of Infection, AIDS, American Journal of Infection Controlmore

Other Topics in Infectious Disease

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