Infectious Disease News Articles

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The latest Infectious Disease news articles, summarized and published daily to keep you current in today's news on bacterial infection, disease treatments, HIV/AIDS, hepatitis and clinical research in infectious diseases and more.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Complications of cesarean deliveries among HIV-infected women in the United States AIDS, October 31, 2014    Clinical Article

2 Linezolid versus vancomycin for the treatment of suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a systematic review employing meta-analysis European Journal of Clinical Pharmacology, October 31, 2014    Evidence Based Medicine    Review Article

3 Harmonization of Bordetella pertussis real-time PCR diagnostics in the US, 2012 Journal of Clinical Microbiology, October 31, 2014    Clinical Article

4 Safety and immunogenicity of a modified-vaccinia-virus-Ankara-based influenza A H5N1 vaccine: A randomised, double-blind phase 1/2a clinical trial The Lancet Infectious Diseases, October 31, 2014    Clinical Article

5 Avoiding the perfect storm: The biologic and clinical case for reevaluating the 7-day expectation for methicillin-resistant staphylococcus aureus bacteremia before switching therapy Clinical Infectious Diseases, October 31, 2014    Clinical Article

6 Effectiveness and cost-effectiveness of potential responses to future high levels of transmitted HIV drug resistance in antiretroviral drug-naive populations beginning treatment: Modelling study and economic analysis The Lancet HIV, October 31, 2014    Clinical Article

7 Progress toward curing HIV infections with hematopoietic stem cell transplantation Clinical Infectious Diseases, October 31, 2014    Clinical Article

8 Insufficient fluconazole exposure in pediatric cancer patients and the need for therapeutic drug monitoring in critically ill children Clinical Infectious Diseases, October 31, 2014    Clinical Article

9 Suppressive effect of interleukin 10 on priming of naive hepatitis C virus-specific CD8+ T cells The Journal of Infectious Diseases, October 31, 2014    Clinical Article

10 Dolutegravir: Clinical and laboratory safety in integrase inhibitor–naive patients HIV Clinical Trials, October 31, 2014    Clinical Article

11 Population pharmacokinetic analysis of tesamorelin in HIV-infected patients and healthy subjects Clinical Pharmacokinetics, October 31, 2014    Clinical Article

12 Emtricitabine/rilpivirine/tenofovir disoproxil fumarate single-tablet regimen: a review of its use in HIV infection Drugs, October 31, 2014    Clinical Article

13 Binding of fusion protein FLSC IgG1 to CCR5 is enhanced by CCR5 antagonist Maraviroc Antiviral Research , October 31, 2014    Clinical Article

14 The CD8+ memory stem T cell (TSCM) subset is associated with improved prognosis in chronic HIV-1 infection Journal of Virology, October 31, 2014    Clinical Article

15 Chemotherapy-related reactivation of hepatitis B infection: Updates in 2013 Full Text World Journal of Gastroenterology, October 31, 2014    Review Article

16 Rapid identification of major Escherichia coli sequence types causing urinary tract and bloodstream infections Journal of Clinical Microbiology, October 31, 2014    Clinical Article

17 An economic model to compare linezolid and vancomycin for the treatment of confirmed methicillin-resistant Staphylococcus aureus nosocomial pneumonia in Germany Full Text Infection and Drug Resistance, October 31, 2014    Clinical Article

18 Penicillin susceptibility breakpoints for Streptococcus pneumoniae and their effect on susceptibility categorisation in Germany (1997–2013) European Journal of Clinical Microbiology & Infectious Diseases, October 31, 2014    Clinical Article

19 Pharmacokinetic and pharmacodynamic properties of calaspargase pegol Escherichia coli L-asparaginase in the treatment of patients with acute lymphoblastic leukemia: Results from Children’s Oncology Group Study Journal of Clinical Oncology, October 31, 2014    Clinical Article

20 Peripheral and local human papillomavirus 16–specific CD8+ T-Cell expansions characterize erosive oral lichen planus Journal of Investigative Dermatology, October 31, 2014    Clinical Article

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Highlights in Infectious Disease

Intermittent ?-lactam bolus therapy less effective than prolonged infusion

Based on a meta-analysis (n=29 studies [2206 patients]) published in the Journal of Antimicrobial Agents, intermittent β-lactam therapy was less effective than prolonged infusion with respect to mortality rate (RR = 0.66) and clinical success (RR = 1.12).

Pre-treatment with EPA decreases incidence of IFN-?-induced depression

As reported in Biological Psychiatry, pre-treatment of HCV-infected patients (n=162) with EPA for 2 weeks resulted in a decreased incidence of IFN-α-induced depression at 24 weeks compared to placebo (10% vs. 30%), and a delayed onset of depression (12.0 weeks vs. 5.3 weeks).

SIRT3 expression improves prognosis in gastric cancer

As reported in Clinical Microbiology & Infection, among 158 adults with community-acquired respiratory failure, nasopharyngeal swabs revealed a RSV infection rate of 4% and an influenza virus infection rate of 15%.

Other Topics in Infectious Disease

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