The Latest Journal Articles in Infectious Disease

1Systematic review with meta-analysis: Comparison between therapeutic regimens for paediatric chronic hepatitis CAlimentary Pharmacology and Therapeutics, May 01, 2015  Evidence Based Medicine  Review Article
2Impaired Th17 polarization of phenotypically naive CD4+ T-cells during chronic HIV-1 infection and potential restoration with early ARTRetrovirology, May 01, 2015  Full Text  Clinical Article
3Spread and persistence of influenza A viruses in waterfowl hosts in the North American Mississippi Migratory FlywayJournal of Virology, May 01, 2015  Clinical Article
4Prevalence of O157:H7 in water sources: An overview on associated diseases, outbreaks and detection methodsDiagnostic Microbiology and Infectious Disease, May 01, 2015  Review Article
5Isavuconazole, micafungin and eight comparator antifungal agents susceptibility profiles for common and uncommon opportunistic fungi collected in 2013: Temporal analysis of antifungal drug resistance using CLSI species-specific clinical breakpoints and proposed epidemiological cutoff valuesDiagnostic Microbiology and Infectious Disease, May 01, 2015  Clinical Article
6Pre-exposure prophylaxis for sexually-acquired HIV risk management: A reviewHIV/AIDS - Research and Palliative Care, May 01, 2015  Full Text  Review Article
7Co-infection as a confounder for the role of Clostridium difficile infection in children with diarrhoea: A summary of the literatureEuropean Journal of Clinical Microbiology & Infectious Diseases, May 01, 2015  Review Article
8Review of meta-analyses of vancomycin compared with new treatments for Gram-positive skin and soft-tissue infections: Are we any clearer?International Journal of Antimicrobial Agents, May 01, 2015  Evidence Based Medicine  Review Article
9Clinical characteristics of HIV patients being referred for liver transplant evaluation: A descriptive cohort studyTransplant Infectious Disease, May 01, 2015  Clinical Article
10Reduction of soluble CD163, substance P, programmed death 1 and inflammatory markers: Phase 1B trial of aprepitant in HIV-1-infected adultsAIDS, May 01, 2015  Clinical Article
1Notes from the field: Campylobacteriosis outbreak associated with consuming undercooked chicken liver pate - Ohio and Oregon, December 2013-January 2014Morbidity and Mortality Weekly Report, May 01, 2015
2Notes from the field: infant botulism caused by clostridium baratii type f - iowa, 2013Morbidity and Mortality Weekly Report, May 01, 2015
3Drug resistant bacteria common for nursing home residents with dementiaThe Society for Healthcare Epidemiology of America News, May 01, 2015
4A new and less toxic HIV drugIDIBELL-Bellvitge Biomedical Research Institute News, May 01, 2015
5WHO report finds systems to combat antibiotic resistance lackingWHO news, May 01, 2015
6Quenching the thirst for clean, safe waterMichigan State University Health News, May 01, 2015
7When good cells go bad: How malaria turns our red blood cells into killersUniversity of Melbourne News, May 01, 2015
8Inflammatory bowel disease: A gut bacterium with beneficial propertiesInserm (Institut national de la santé et de la recherche médicale), May 01, 2015
9Novel cell therapy from 'naive' cells recognizes, attacks high-risk viruses for first time in cord blood transplant patientsBaylor College of Medicine News, May 01, 2015
10Screening for HIV in GP surgeries leads to increased and earlier diagnosisQueen Mary University of London News, May 01, 2015

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Pre-treatment with EPA decreases incidence of IFN-?-induced depression

As reported in Biological Psychiatry, pre-treatment of HCV-infected patients (n=162) with EPA for 2 weeks resulted in a decreased incidence of IFN-α-induced depression at 24 weeks compared to placebo (10% vs. 30%), and a delayed onset of depression (12.0 weeks vs. 5.3 weeks).

SIRT3 expression improves prognosis in gastric cancer

As reported in Clinical Microbiology & Infection, among 158 adults with community-acquired respiratory failure, nasopharyngeal swabs revealed a RSV infection rate of 4% and an influenza virus infection rate of 15%.

Intermittent ?-lactam bolus therapy less effective than prolonged infusion

Based on a meta-analysis (n=29 studies [2206 patients]) published in the Journal of Antimicrobial Agents, intermittent β-lactam therapy was less effective than prolonged infusion with respect to mortality rate (RR = 0.66) and clinical success (RR = 1.12).

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Clinical Pearls

Clinical Pearl from Smartest DocRoughly 5 percent of hematopoietic stem cell transplant patients develop invasive fungal infections even with antifungal therapy.

Clinical Pearl from Smartest DocScreening und Behandlung latenter TBC-Infektionen wird bei Transplantationskandidaten empfohlen.

Clinical Pearl from Smartest DocA pregnant patient who is a chronic hepatitis B virus carrier with a positive HBeAg status is at increased risk of preterm birth and low birth weight.

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