Infectious Disease News Articles

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The latest Infectious Disease news articles, summarized and published daily to keep you current in today's news on bacterial infection, disease treatments, HIV/AIDS, hepatitis and clinical research in infectious diseases and more.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Amphotericin B deoxycholate nasal spray administered to hematopoietic stem cell recipients with prior fungal colonization of the upper airway passages is associated with low rates of invasive fungal infection Transplant Infectious Disease, January 26, 2015    Clinical Article

2 Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial The Lancet, January 26, 2015    Evidence Based Medicine    Clinical Article

3 Randomized trial of interferon- and ribavirin-free ombitasvir/paritaprevir/ritonavir in treatment-experienced HCV-infected patients Hepatology, January 26, 2015    Clinical Article

4 Safety and immunogenicity of a 13-valent pneumococcal conjugate vaccine manufactured with and without polysorbate 80 given to healthy infants at 2, 3, 4 and 12 months of age The Pediatric Infectious Disease Journal, January 26, 2015    Clinical Article

5 High-dose vitamin D3 supplementation in children and young adults with HIV: a randomized, placebo-controlled trial The Pediatric Infectious Disease Journal, January 26, 2015    Clinical Article

6 All-oral 12-week treatment with daclatasvir plus sofosbuvir in patients with hepatitis C virus genotype 3 infection: ALLY-3 Phase 3 Study Hepatology, January 26, 2015    Clinical Article

7 Update on the management of Candida infections in preterm neonates ADC Fetal & Neonatal Edition, January 26, 2015    Review Article

8 Simeprevir and sofosbuvir for treatment of chronic hepatitis C infection Clinical Therapeutics, January 26, 2015    Clinical Article

9 A randomized trial to evaluate the efficacy of a web-based hiv behavioral intervention for high-risk african american women AIDS and Behavior, January 26, 2015    Clinical Article

10 Changes in sexual behavior of HIV-infected older adults enrolled in a clinical trial of standalone group psychotherapies targeting depression AIDS and Behavior, January 26, 2015    Clinical Article

11 Temporal trends in age at HIV diagnosis in cohorts in the United States, the Caribbean, and Central and South America AIDS and Behavior, January 26, 2015    Clinical Article

12 Efficacy of etravirine combined with darunavir or other ritonavir-boosted protease inhibitors in HIV-1-infected patients: an observational study using pooled European cohort data HIV Medicine, January 26, 2015    Clinical Article

13 Computer-aided assessment of hepatic contour abnormalities as an imaging biomarker for the prediction of hepatocellular carcinoma development in patients with chronic hepatitis C European Journal of Radiology, January 26, 2015    Clinical Article

14 Peri-prosthetic infection -- An algorithmic approach to diagnosis and management Orthopaedics and Trauma, January 26, 2015    Review Article    Clinical Article

15 Clinicoradiologic response of neurologic tuberculous mass lesions in children treated with thalidomide The Pediatric Infectious Disease Journal, January 26, 2015    Clinical Article

16 Safety, tolerability and immunogenicity of 15-valent pneumococcal conjugate vaccine in toddlers previously vaccinated with 7-valent pneumococcal conjugate vaccine The Pediatric Infectious Disease Journal, January 26, 2015    Clinical Article

17 Perinatal pharmacokinetics of azithromycin for cesarean prophylaxis American Journal of Obstetrics and Gynecology, January 26, 2015    Clinical Article

18 IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy Journal of Infection, January 26, 2015    Clinical Article

19 Challenges of disseminating clinical practice guidelines in a weak health system: The case of HIV and infant feeding recommendations in Tanzania Full Text International Breastfeeding Journal, January 26, 2015    Clinical Article

20 Bacteraemia and antibiotic-resistant pathogens in community acquired pneumonia: Risk and prognosis European Respiratory Journal , January 26, 2015    Clinical Article

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Highlights in Infectious Disease

Short-term valacyclovir therapy does not reduce HIV acquisition risk in HSV-2 infected women

As reported in the Journal of Infectious Diseases, short-term treatment of HSV-2 infected, HIV non-infected women (n=30) with valacyclovir (1 g qd x 2 months) had no effect on cervical CD4+ T cells, dendritic cells, or pro-inflammatory cytokines, but increased CCR5 (HIV co-receptor) and CD69 (activation marker).

Chronic HCV infections are under-reported

As reported in Clinical Infectious Diseases, of 12M death certificates only one-fifth of the 0.5% of patients with HCV had HCV listed on the death certificate. Moreover, two-thirds of the patients had pre-mortem signs of chronic liver disease.

HIV viremia associated with increased risk for NHL

As reported in Modern Pathology, CDX2 expression is associated with low-grade small intestinal adenocarcinomas, decreased nodal metastases, and decreased perineural invasion, while MUC1 expression is associated with high-grade tumors, and nodular and infiltrative tumors. The CDX2+/MUC1- immunophenotype is associated with increased survival.

Other Topics in Infectious Disease

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