Infectious Disease News Articles

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The latest Infectious Disease news articles, summarized and published daily to keep you current in today's news on bacterial infection, disease treatments, HIV/AIDS, hepatitis and clinical research in infectious diseases and more.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 HPV and lung cancer risk: A meta-analysis Journal of Clinical Virology, October 22, 2014    Evidence Based Medicine

2 Sofosbuvir-based treatment regimens for chronic, genotype 1 hepatitis C virus infection in U.S. incarcerated populations: A cost-effectiveness analysis Annals of Internal Medicine, October 22, 2014    Clinical Article

3 Accuracy of urinary human papillomavirus testing for presence of cervical HPV: systematic review and meta-analysis BMJ, October 22, 2014    Evidence Based Medicine    Review Article

4 Human papillomavirus vaccine uptake among males 11–26 years in United States: Findings from the National Health and Nutrition Examination Survey, 2011-2012 Vaccine , October 22, 2014    Clinical Article

5 Mutation-driven β-lactam resistance mechanisms among contemporary ceftazidime-nonsusceptible Pseudomonas aeruginosa isolates from U.S. hospitals Antimicrobial Agents and Chemotherapy, October 22, 2014    Clinical Article

6 Infrequent development of resistance in genotype 1-6 hepatitis C virus-infected subjects treated with sofosbuvir in phase 2 and 3 clinical trials Clinical Infectious Diseases, October 22, 2014    Clinical Article

7 Hepatitis C virus (HCV) antibody dynamics following acute HCV infection and reinfection among HIV-infected men who have sex with men Clinical Infectious Diseases, October 22, 2014    Clinical Article

8 Acquired rifampicin resistance in thrice-weekly antituberculosis therapy: Impact of HIV and antiretroviral therapy Clinical Infectious Diseases, October 22, 2014    Clinical Article

9 Management of chronic hepatitis B infection Archives of Diseases in Childhood, October 22, 2014    Review Article    Clinical Guideline

10 Predictors and long-term outcome of seizures in human immuno-deficiency virus (HIV)-negative Cryptococcal meningitis Full Text BMC Neurology, October 22, 2014    Clinical Article

11 Early preservation of CXCR5+ PD-1+ helper T cells and B cell activation predict the breadth of neutralizing antibody responses in chronic HIV-1 infection Journal of Virology, October 22, 2014    Clinical Article

12 Estimating chlamydia screening coverage: A comparison of self-report and health care effectiveness data and information set measures Sexually Transmitted Diseases, October 22, 2014    Clinical Article

13 Framework for optimisation of the clinical use of colistin and polymyxin B: The Prato polymyxin consensus The Lancet Infectious Diseases, October 22, 2014    Clinical Article

14 Comparison of two databases to detect potential drug–drug interactions between prescriptions of HIV/AIDS patients in critical care Journal of Clinical Pharmacy and Therapeutics, October 22, 2014    Clinical Article

15 Correlation between body temperature and survival rate in patients with hospital-acquired bacteremia: A prospective observational study Biological Research For Nursing, October 22, 2014    Clinical Article

16 Internet-based cohort study of HIV testing over 1 year among men who have sex with men living in England and exposed to a social marketing intervention promoting testing Sexually Transmitted Infections, October 22, 2014    Clinical Article

17 The impact of hepatitis B virus x protein and microRNAs in hepatocellular carcinoma: A comprehensive analysis Tumor Biology, October 22, 2014    Review Article

18 Impact of clinical decision support on receipt of antibiotic prescriptions for acute bronchitis and upper respiratory tract infection JAMIA, October 22, 2014    Clinical Article

19 Mycobacterium tuberculosis promotes Th17 expansion via regulation of human dendritic cells toward a high CD14 and low IL-12p70 phenotype that reprograms upon exogenous IFN-γ International Immunology, October 22, 2014    Clinical Article

20 Non-classical MHC-I human leukocyte antigen (HLA-G) in hepatotropic viral infections and in hepatocellular carcinoma Human Immunology, October 22, 2014    Review Article

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Highlights in Infectious Disease

Intermittent ?-lactam bolus therapy less effective than prolonged infusion

Based on a meta-analysis (n=29 studies [2206 patients]) published in the Journal of Antimicrobial Agents, intermittent β-lactam therapy was less effective than prolonged infusion with respect to mortality rate (RR = 0.66) and clinical success (RR = 1.12).

Pre-treatment with EPA decreases incidence of IFN-?-induced depression

As reported in Biological Psychiatry, pre-treatment of HCV-infected patients (n=162) with EPA for 2 weeks resulted in a decreased incidence of IFN-α-induced depression at 24 weeks compared to placebo (10% vs. 30%), and a delayed onset of depression (12.0 weeks vs. 5.3 weeks).

Short-term valacyclovir therapy does not reduce HIV acquisition risk in HSV-2 infected women

As reported in the Journal of Infectious Diseases, short-term treatment of HSV-2 infected, HIV non-infected women (n=30) with valacyclovir (1 g qd x 2 months) had no effect on cervical CD4+ T cells, dendritic cells, or pro-inflammatory cytokines, but increased CCR5 (HIV co-receptor) and CD69 (activation marker).

Other Topics in Infectious Disease

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