SIRT3 expression improves prognosis in gastric cancer
As reported in Clinical Microbiology & Infection, among 158 adults with community-acquired respiratory failure, nasopharyngeal swabs revealed a RSV infection rate of 4% and an influenza virus infection rate of 15%.
Short-term valacyclovir therapy does not reduce HIV acquisition risk in HSV-2 infected women
As reported in the Journal of Infectious Diseases, short-term treatment of HSV-2 infected, HIV non-infected women (n=30) with valacyclovir (1 g qd x 2 months) had no effect on cervical CD4+ T cells, dendritic cells, or pro-inflammatory cytokines, but increased CCR5 (HIV co-receptor) and CD69 (activation marker).
Intermittent ?-lactam bolus therapy less effective than prolonged infusion
Based on a meta-analysis (n=29 studies [2206 patients]) published in the Journal of Antimicrobial Agents, intermittent β-lactam therapy was less effective than prolonged infusion with respect to mortality rate (RR = 0.66) and clinical success (RR = 1.12).