Repeated dengue shock syndrome and ‘dengue myocarditis’ responding dramatically to a single dose of methyl prednisolone
International Journal of Infectious Diseases, 04/25/2012
Premaratna R et al. – Authors report the case of a 14–year–old boy with dengue who developed three episodes of severe hemodynamic compromise while having high fever, ‘myocarditis’, third space fluid accumulation, progressive reduction in urine output, and altered mentation, who made a dramatic recovery following a single dose of intravenous methyl prednisolone. Results justify a well powered randomized controlled trial to evaluate the efficacy of this treatment in severe dengue.