CD28-Negative CD4+ and CD8+ T-cells in ART-Naive HIV-Infected Adults Enrolled in ACTG Studies

The Journal of Infectious Diseases, 04/13/2012

Effective ART reduced the proportion of CD28– T–cells. However, levels remained abnormally high and closer to levels in older HIV–uninfected individuals. This finding may inform future research of increased rates of age–associated disease in HIV–infected adults.

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