Rush R et al. – The authors report two cases of fulminant toxoplasmic retinochoroiditis following intravitreal triamcinolone acetonide (IVTA) administration. Aqueous tap polymerase chain reactions were found positive for Toxoplasma gondii in both cases. In conclusion, IVTA administration can lead to fulminant toxoplasmic retinochoroiditis even when used with appropriate anti–toxoplasmic therapy. Extreme caution should be exercised while administering depot corticosteroids in eyes with panuveitis of unknown origin.