Ketoamide Resistance and Hepatitis C Virus Fitness in Val55 Variants of the NS3 Serine Protease
Antimicrobial Agents and Chemotherapy, 04/06/2012
Welsch C et al. – Reduced structural flexibility could impact the Val55 variant's ability to adapt for NS3 domain–domain interaction and might explain the virus yield drop observed in variant strains.



