Clindamycin vs first-generation cephalosporins for acute osteoarticular infections of childhood - prospective quasi-randomized controlled trial
Clinical Microbiology and Infection, 08/16/2011
Peltola H et al. – Clindamycin or a first–generation cephalosporin, administered mostly orally, perform equally well in childhood osteoarticular infections, provided high doses and q.i.d. administration is used. Since most methicillin–resistant staphylococci remain clindamycin–sensitive, clindamycin remains an option instead of costly alternatives.