Value of the Serum Procalcitonin Level to Guide Antimicrobial Therapy for Patients with Ventilator-Associated Pneumonia
Seminars in Respiratory and Critical Care Medicine, 05/03/2011
Luyt CE et al. – Two recent studies showed that a procalcitonin–based strategy led to less antibiotic consumption by VAP patients, compared with a conventional strategy, with no adverse outcome. Accordingly, for VAP patients, procalcitonin may be used to stop antibiotics as early as day 3 after their initiation, if its concentration is <0.5 ng/mL or has decreased by >80%, compared with the first peak concentration.