Long term Hepatitis B surface antigen decay in HIV-1/HBV coinfected adults initiating a tenofovir containing regimen

Journal of Clinical Microbiology, 07/05/2012

The mean HBsAg decay was 0.38 Log10 IU/ml/year (95% CI: 0.71–0.05) in 18 patients with sustained plasma HIV–1 RNA suppression and 0.15 Log10 IU/ml/year (0.21–0.09) in 12 patients experiencing HIV–1 virologic failure due to suboptimal adherence to ARV (p=0.17). They estimated that six patients will attain HBsAg value below 10 IU/ml after ten years of treatment.

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