Early prediction of treatment efficacy in second-stage gambiense human african trypanosomiasis

PLoS Neglected Tropical Diseases, 06/08/2012

The 6–month CSF leucocytes counts (CSFLC) can predict outcome with some limitations. Two–step algorithms enhance the accuracy but impose 12–month follow–up for some patients. For early estimation of efficacy in clinical trials and for individual patients in the field, several options exist that can be used according to priorities.

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