The Combination of Doripenem and Colistin Is Bactericidal and Synergistic against Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae
Antimicrobial Agents and Chemotherapy, 05/17/2012Jernigan MG et al.
Among colistin– and pan–drug–resistant isolates, synergy was identified in 60 and 67%, respectively. All other combinations were inferior. Authors are currently evaluating the combination of doripenem and colistin as a frontline therapy for KPC infection.
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