Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for caspofungin susceptibility testing of Candida and Aspergillus species

Journal of Clinical Microbiology, 05/03/2012

Complete essential agreement was observed with the CLSI reference method, with categorical agreement for 94.1% of the Candida isolates tested. Thus, MALDI–TOF MS is a reliable and accurate method to detect fungal isolates with reduced caspofungin susceptibility.

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