Sequencing-based detection of drug-resistant Mycobacterium tuberculosis in patients with spinal tuberculosis

Archives of Orthopaedic and Trauma Surgery, 04/10/2012

The results indicated that PCR and DNA sequencing are rapid, sensitive, and specific methods for the detection of drug–resistant genes of M. tuberculosis in patients with spinal tuberculosis. This method may provide critical evidence for the clinical treatment of tuberculosis when it is applied in combination with bacterial culture.

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