Topical permethrin and oral ivermectin in the management of scabies: A prospective, randomized, double blind, controlled study

Indian Journal of Dermatology, Venereology and Leprology , 08/22/2011

Cure rate in three treatment groups at the end of 4 weeks was 94.7% (A), 90% (B), 89.7%(C), and thus all three treatment modalities were equally efficacious. However, at 1 week follow up, group A patients reported better improvement in both lesion count and pruritus. Both permethrin and ivermectin in both single and two dose regimen are equally efficacious and well tolerated in scabies. However, permethrin has a rapid onset of action.

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