Infectious Disease News & Articles

1 Persistent nasal methicillin-resistant staphylococcus aureus carriage in hemodialysis outpatients: a predictor of worse outcome BMC Nephrology, May 13, 2013
Schmid H et al. - Nasal colonization with methicillin-resistant Staphylococcus aureus (mrsa) is a well defined risk factor for subsequent bacteremia and death in various groups of patients, but its impact on outcome in patients receiving long-term hemodialysis (HD) is under debate. It was found that nasal mrsa carriage with failure of mupirocin decolonization was associated with increased mortality despite a lack of overt clinical signs of infection. Further studies are ...

2 MRSA infection in the neonatal intensive care unit Expert Review of Anti-infective Therapy, May 7, 2013
Giuffre M et al. - Methicillin-resistant Staphylococcus aureus (mrsa) is well known as one of the most frequent etiological agents of healthcare-associated infections. The epidemiology of mrsa is evolving with emergence of community-associated mrsa, the clonal spread of some successful clones, their spillover into healthcare settings and acquisition of antibacterial drug resistances. Surveillance, prevention and control strategies and clinical management have been ...

3 Interventions for the eradication of methicillin-resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis Cochrane Reviews, March 19, 2013
Lo DKH et al. - Cystic fibrosis is an inherited recessive disorder of chloride transport that is characterised by recurrent and persistent pulmonary infections from resistant organisms that result in lung function deterioration and early mortality in sufferers. Clear guidance for the eradication of mrsa in cystic fibrosis, supported by robust evidence from good quality trials, is urgently needed. To evaluate the effectiveness of treatment regimens designed to eradicate mrsa and to ...

4 Prognosis of patients with methicillin-resistant Staphylococcus aureus bloodstream infection treated with teicoplanin: a retrospective cohort study investigating effect of teicoplanin minimum inhibitory concentrations BMC Infectious Diseases, April 30, 2013
Wang JT et al. - The present study was designed to investigate whether teicoplanin minimum inhibitory concentrations (MICs) of methicillin-resistant Staphylococcus aureus (mrsa) isolates play a role in the prognosis of patient with teicoplanin-treated mrsa bloodstream infection (BSI). The current study didn’t find a significant role for teicoplanin MICs in the prognosis of adult patients with teicoplanin-treated mrsa BSI. Methods Between 1 January 2006 and 31 ...

5 Molecular epidemiology and characterization of virulence genes of community-acquired and hospital-acquired methicillin-resistant Staphylococcus aureus isolates in Colombia International Journal of Infectious Diseases, May 2, 2013
Portillo BC et al. - To determine the molecular epidemiology and presence of virulence genes in community-acquired (CA) and hospital-acquired (HA) methicillin-resistant Staphylococcus aureus (mrsa) isolates and their relationship to clinical outcomes. The study confirms that three clones of mrsa predominantly circulate in Colombia: a Chilean clone, a pediatric clone that causes HA-mrsa infections, and a USA300-related clone (SCCmec IVc) in CA-mrsa ...

6 Prevalence of methicillin-resistant Staphylococcus aureus in skin and soft tissue infections in patients presenting to Canadian emergency departments Canadian Journal of Emergency Medicine, May 3, 2013
Borgundvaag B et al. - Community-associated methicillin-resistant Staphylococcus aureus (mrsa) is an increasingly common cause of skin and soft tissue infection (SSTI) worldwide. The prevalence of mrsa in SSTIs across Canada has not been well described. Studies in the United States have shown significant geographic variability in the prevalence of mrsa. This study characterizes the geographic prevalence and microbiology of mrsa in patients presenting to Canadian emergency ...

7 Use of Copper Alloy for Preventing Transmission of Methicillin-resistant Staphylococcus aureus Contamination in the Dermatology Ward Acta Dermato-Venereologica, May 17, 2013
Niiyama N et al. - Metallic copper has been shown significantly to reduce methicillin-resistant Staphylococcus aureus (mrsa) contamination of the ambient surroundings of the beds of mrsa-carrying patients in dermatology wards. The aim of this study was to determine whether a bed sheet made of copper-coated film will reduce the spread of mrsa contamination in the environment of a heavily-colonized patient. The bacterial count was highest on the bed sheet. mrsa cell ...

8 Socioeconomic implications of pediatric cervical methicillin-resistant staphylococcus aureus infections pediatric cervical mrsa infections JAMA Otolaryngology—Head & Neck Surgery, February 4, 2013
McCormick ME et al. - The study aims to study cervical methicillin-resistant Staphylococcus aureus (mrsa) infections using a national database with the goal of providing normative data and identifying variations in resource utilization. Cervical mrsa infections have a large socioeconomic impact across the nation. There are differences among the various races in resource utilization. Younger children have longer hospitalizations, are more likely to need surgery, and require more ...

9 ST9 MRSA strains carrying a variant of type IX SCCmec identified in the Thai community BMC Infectious Diseases, May 13, 2013
Lulitanond A et al. - Infections caused by methicillin-resistant Staphylococcus aureus (mrsa) in Thailand occur most frequently in healthcare facilities. However, reports of community-associated mrsa are limited. The SCCmecIX-ST9 mrsa clones of distinct SCCmec subtypes might have emerged in the Thai community and might also have disseminated into the hospital.

10 Meticillin-resistant Staphylococcus aureus in elderly residents of care homes: colonization rates and molecular epidemiology Journal of Hospital Infection, February 1, 2013
Horner C et al. - Meticillin-resistant Staphylococcus aureus (mrsa) is a significant cause of mortality and morbidity in healthcare and community settings; however, there is a paucity of large-scale, longitudinal studies monitoring the occurrence of mrsa in the care home setting. The molecular epidemiology of mrsa in care homes is complex and dynamic. There was a high, consistent prevalence of mrsa nasal colonization, dominated by healthcare-associated strains. ...