Infectious Disease News Articles

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The latest Infectious Disease news articles, summarized and published daily to keep you current in today's news on bacterial infection, disease treatments, HIV/AIDS, hepatitis and clinical research in infectious diseases and more.

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Ranked, sorted, and summarized by MDLinx editors from the latest literature

1 Adherence to HIV postexposure prophylaxis: A systematic review and meta-analysis AIDS, November 21, 2014    Evidence Based Medicine    Review Article

2 Dose-response for starting and stopping HIV pre-exposure prophylaxis (PrEP) for MSM Clinical Infectious Diseases, November 21, 2014    Clinical Article

3 Effect of corticosteroid therapy on influenza-related mortality: A systematic review and meta-analysis The Journal of Infectious Diseases, November 21, 2014    Evidence Based Medicine    Review Article

4 Gestational syphilis and stillbirth in Latin America and the Caribbean International Journal of Gynecology & Obstetrics, November 21, 2014    Clinical Article

5 Gay and bisexual men engage in fewer risky sexual behaviors while traveling internationally: A cross-sectional study in San Francisco Sexually Transmitted Infections, November 21, 2014    Clinical Article

6 Vitamin D supplementation is associated with reduced immune activation levels in HIV-1-infected patients on suppressive antiretroviral therapy AIDS, November 21, 2014    Clinical Article

7 Efficacy and safety of the mosquitocidal drug ivermectin to prevent malaria transmission after treatment: A double-blind, randomized, clinical trial Clinical Infectious Diseases, November 21, 2014    Clinical Article

8 The interaction between sickle cell disease and HIV infection: A systematic review Clinical Infectious Diseases, November 21, 2014    Review Article

9 Examining the risks of cardiac arrhythmia and mortality among new-generation macrolides, fluoroquinolones, and beta-lactam/beta-lactamase inhibitor: A nationwide study Clinical Infectious Diseases, November 21, 2014

10 Cardiovascular manifestations of HIV infection in children European Journal of Preventive Cardiology, November 21, 2014    Clinical Article

11 Human semen contains exosomes with potent anti-HIV-1 activity Full Text Retrovirology, November 21, 2014    Clinical Article

12 Changes in the incidence of severe thrombocytopenia and its predisposing conditions in HIV-infected patients since the introduction of highly active antiretroviral therapy Journal of Acquired Immune Deficiency Syndromes, November 21, 2014    Clinical Article

13 Nutrition risk and complications in HIV/AIDS: the impact of food insecurity Topics in Clinical Nutrition, November 21, 2014    Clinical Article

14 Relationship of HIV reservoir characteristics with immune status and viral rebound kinetics in an HIV therapeutic vaccine study AIDS, November 21, 2014    Clinical Article

15 Autologous aldrithiol-2-inactivated HIV-1 combined with polyinosinic-polycytidylic acid–poly-l-lysine carboxymethylcellulose as a vaccine platform for therapeutic dendritic cell immunotherapy Vaccine , November 21, 2014    Clinical Article

16 Evaluation of an intervention to improve blood culture practices: A cluster randomised trial European Journal of Clinical Microbiology & Infectious Diseases, November 21, 2014    Clinical Article

17 Infections and infestations of the skin Paediatrics and Child Health, November 21, 2014    Review Article

18 Current perioperative practice patterns for minimizing surgical site infection during rhinologic procedures International Forum of Allergy & Rhinology, November 21, 2014    Clinical Article

19 Predictive utility of prior positive urine cultures Clinical Infectious Diseases, November 21, 2014    Clinical Article

20 Validation of a commercial dry-form broth microdilution device (Sensititre) for testing tedizolid, a new oxazolidinone Journal of Clinical Microbiology, November 21, 2014    Clinical Article

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Highlights in Infectious Disease

Chronic HCV infections are under-reported

As reported in Clinical Infectious Diseases, of 12M death certificates only one-fifth of the 0.5% of patients with HCV had HCV listed on the death certificate. Moreover, two-thirds of the patients had pre-mortem signs of chronic liver disease.

Pre-treatment with EPA decreases incidence of IFN-?-induced depression

As reported in Biological Psychiatry, pre-treatment of HCV-infected patients (n=162) with EPA for 2 weeks resulted in a decreased incidence of IFN-α-induced depression at 24 weeks compared to placebo (10% vs. 30%), and a delayed onset of depression (12.0 weeks vs. 5.3 weeks).

Hospital readmission rate in patients discharged on parenteral antibiotics

As reported in Clinical Infectious Diseases, the hospital readmission rate for patients (n=782) discharged on parenteral antibiotics was 26%. The mean patient age was 58 years. The leading diagnoses were bacteremia, osteomyelitis, and pyelonephritis. The indications for readmission included non-infection related (30%), worsening symptoms (29%), and new infections (19%). The ORs for readmission factors were as follows: each decade increase in age, 1.09; aminoglycoside use, 2.33; resistant organism, 1.57; and number of hospital discharges in prior 12 months, 1.20.

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