The Latest Journal Articles in Infectious Disease

1The epidemiology of acute hepatitis B in the United States from population-based surveillance, 2006-2011Clinical Infectious Diseases, April 24, 2015  Clinical Article
2Mycoplasma genitalium infection and female reproductive tract disease: A meta-analysisClinical Infectious Diseases, April 24, 2015  Evidence Based Medicine
3Low vitamin D status among pregnant Latin American and Caribbean women with HIV infectionInternational Journal of Gynecology & Obstetrics, April 24, 2015  Clinical Article
4A meta-analytic assessment of the risk of chronic kidney disease in patients with chronic hepatitis C virus infectionJournal of Viral Hepatitis, April 24, 2015  Evidence Based Medicine  Review Article
5Association between educational level and risk of cancer in HIV-infected individuals and the background population: Population-based cohort study 1995-2011The Journal of Infectious Diseases, April 24, 2015  Clinical Article
6Comparative effectiveness of beta-lactams versus vancomycin for treatment of methicillin-susceptible Staphylococcus aureus bloodstream infections among 122 hospitalsClinical Infectious Diseases, April 24, 2015  Clinical Article
7Impact of daily cotrimoxazole on clinical malaria and asymptomatic parasitemias in HIV-exposed uninfected infantsClinical Infectious Diseases, April 24, 2015  Clinical Article
8Vitamin D sufficiency and staphylococcus aureus infection in childrenThe Pediatric Infectious Disease Journal, April 24, 2015  Clinical Article
9Predisposing factors for positive D-Xylose breath test for evaluation of small intestinal bacterial overgrowth: A retrospective study of 932 patientsWorld Journal of Gastroenterology, April 24, 2015  Full Text  Clinical Article
10Clostridium difficile infection among hospitalized HIV-infected individuals: Epidemiology and risk factors: Results from a case-control study (2002-2013)BMC Infectious Diseases, April 24, 2015  Full Text  Clinical Article
1Viral proteins may regulate human embryonic developmentStanford School of Medicine News, April 24, 2015
2Using human fat cells to fight infectionQueensland Brain Insitute News, April 24, 2015
3Researchers produce first atlas of airborne microbes across United StatesUniversity of Colorado at Boulder News, April 24, 2015
4Fake malaria drugs not as common as previously reportedLondon School of Hygiene & Tropical Medicine News, April 24, 2015
5Study sheds new light on a crucial enzyme for the immune responseUniversite de Montreal News, April 24, 2015
6First case of rabies in over a decade: Lessons for healthcare personnelAmerican Society for Microbiology News, April 24, 2015
7University of Maryland School of Medicine scientist helps discover never-before-seen tick-borne diseaseUniversity of Maryland School of Medicine News, April 24, 2015
8UTMB researchers develop Ebola treatment effective three days after infectionUniversity of Texas Medical Branch at Galveston, April 24, 2015
9Trial of statin therapy to reduce HIV-associated cardiovascular risk open for enrollmentMassachusetts General Hospital, April 24, 2015
10World Malaria Day: Call to close gaps in prevention and treatment to defeat malariaWHO news, April 24, 2015

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Hospital readmission rate in patients discharged on parenteral antibiotics

As reported in Clinical Infectious Diseases, the hospital readmission rate for patients (n=782) discharged on parenteral antibiotics was 26%. The mean patient age was 58 years. The leading diagnoses were bacteremia, osteomyelitis, and pyelonephritis. The indications for readmission included non-infection related (30%), worsening symptoms (29%), and new infections (19%). The ORs for readmission factors were as follows: each decade increase in age, 1.09; aminoglycoside use, 2.33; resistant organism, 1.57; and number of hospital discharges in prior 12 months, 1.20.

HIV viremia associated with increased risk for NHL

As reported in Modern Pathology, CDX2 expression is associated with low-grade small intestinal adenocarcinomas, decreased nodal metastases, and decreased perineural invasion, while MUC1 expression is associated with high-grade tumors, and nodular and infiltrative tumors. The CDX2+/MUC1- immunophenotype is associated with increased survival.

Short-term valacyclovir therapy does not reduce HIV acquisition risk in HSV-2 infected women

As reported in the Journal of Infectious Diseases, short-term treatment of HSV-2 infected, HIV non-infected women (n=30) with valacyclovir (1 g qd x 2 months) had no effect on cervical CD4+ T cells, dendritic cells, or pro-inflammatory cytokines, but increased CCR5 (HIV co-receptor) and CD69 (activation marker).

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Clinical Pearls

Clinical Pearl from Smartest DocESR and CRP are routinely used to diagnose periprosthetic joint infection but lack specificity.

Clinical Pearl from Smartest DocHepatitis C clearance with sofosbuvir and ribavirin alters peripheral and intrahepatic lipid metabolism.

Clinical Pearl from Smartest DocHäufig werden Breitspektrumantibiotika eingesetzt, sogar wenn es keine klinischen Anzeichen einer Infektion gibt.

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