SIRT3 expression improves prognosis in gastric cancer
As reported in Clinical Microbiology & Infection, among 158 adults with community-acquired respiratory failure, nasopharyngeal swabs revealed a RSV infection rate of 4% and an influenza virus infection rate of 15%.
Intermittent ?-lactam bolus therapy less effective than prolonged infusion
Based on a meta-analysis (n=29 studies [2206 patients]) published in the Journal of Antimicrobial Agents, intermittent β-lactam therapy was less effective than prolonged infusion with respect to mortality rate (RR = 0.66) and clinical success (RR = 1.12).
Hospital readmission rate in patients discharged on parenteral antibiotics
As reported in Clinical Infectious Diseases, the hospital readmission rate for patients (n=782) discharged on parenteral antibiotics was 26%. The mean patient age was 58 years. The leading diagnoses were bacteremia, osteomyelitis, and pyelonephritis. The indications for readmission included non-infection related (30%), worsening symptoms (29%), and new infections (19%). The ORs for readmission factors were as follows: each decade increase in age, 1.09; aminoglycoside use, 2.33; resistant organism, 1.57; and number of hospital discharges in prior 12 months, 1.20.