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Bulled N et al. – The purpose of this paper is to extend awareness of the grave risks of multiperson syringe use by examining the role of this behavior in the development of infectious disease syndemics. The term syndemics refers to the clustering, often due to noxious social conditions, of two or more diseases in a population resulting in adverse disease synergies that impact human life and well–being. The contemporary appearance and spread of identified syringe–mediated syndemics, and the potential for the emergence of future syringe–mediated syndemics, both of which are reviewed in this paper, underline the importance of public health measures designed to limit syringe–related disease transmission.

Exclusive Author Commentary
Nicola Bulled and Merrill Singer, 11/06/09

We are becoming increasingly aware of the importance of syndemics--comorbid adversely interacting diseases--in adding to the health burden of populations and the clinical challenges they create for health care providers. Nonmedical and improper clinical use of syringes is proving to be significant pathways for the spread of interacting infectious diseases. It is critical that health care providers treating syringe using patients (e.g., illicit injection drug users, injection vitamin users, and others) be aware of the locally present diseases beyond HIV/AIDS that can be transmitted in this fashion. Treatment for interacting diseases is complicated by both unusual presentation (which complicates diagnosis) and iatrogenic response (as treatment for one infection may exacerbate a comorbid condition). Because of syndemic interaction there is increased public health value in the diffusion of harm reduction disease prevention approaches like syringe exchange.

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