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What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity
Malaria Journal, 10/29/09
Kinyanjui SM et al. – Failure to distinguish between individuals who do not get a clinical episode during follow–up because they were unexposed and those who are genuinely immune undermines the ability to assign a protective role to immune responses against malaria. The brevity of antibodies responses makes it difficult to assign the true serological status of an individual at any given time, i.e. those positive at a survey may be negative by the time they encounter the next infection.
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