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Acyclovir: a new use for an old drug
Current Opinion in Infectious Diseases, 10/28/09
Vanpouille C et al. – Recent studies have shown that although ACV therapy does not prevent HIV–1 transmission, it decreases plasma, genital, rectal, and seminal HIV–1 RNA levels. The decrease of HIV–1 load has been believed to be the result of an indirect mechanism and explained by reduction of HSV–2–mediated inflammation. The discovery of the direct inhibitory activity of ACV on HIV–1 reverse transcriptase brings new insights into the interpretation of these results. Also, it is important to understand why HSV–2–suppressive therapy with ACV did not reduce HIV–1 acquisition/transmission.
Today in Antimicrobials...keeping you current
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Drugs for preventing malaria in travellers
Cochrane Reviews, 10/23/09
H1N1 Vaccine Production, Availability Increasing Slowly
American Family Physician, 11/02/09
Antibiotic Use in Neonatal Intensive Care Units and Adherence With Centers for Disease Control and Prevention 12 Step Campaign to Prevent Antimicrobial Resistance
The Pediatric Infectious Disease Journal, 10/29/09
Today in HIV/Immunodeficiency...keeping you current
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Alternative Dosage of Zidovudine in Infants Exposed to Maternal Human Immunodeficiency Virus Infection
The Pediatric Infectious Disease Journal, 10/26/09
Interventions for HIV-associated nephropathy
Cochrane Reviews, 10/20/09
Bone health in HIV infection
British Medical Bulletin, 10/30/09
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