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Kuper KM et al. – This primer describes the common antimicrobial susceptibility tests used in the clinical microbiology laboratory and reviews how subtle differences in testing methods and technique can influence reported results. Clinicians who have a thorough understanding of qualitative and quantitative methods, automated susceptibility testing systems, and commonly used screening and confirmatory tests for antibiotic–resistant organisms can strengthen institutional antibiotic stewardship programs and improve patient outcomes.

Exclusive Author Commentary
Kristi M. Kuper, 11/07/09

Antimicrobial susceptibility testing (AST) can be a powerful tool in the war against infectious diseases. It is very helpful in guiding appropriate therapy and supports antibiotic stewardship programs. On the converse, misinterpretation of AST info can result in inappropriate anti-infective therapy selection and negative clinical outcomes. Because many clinicians receive limited training in this area and there are few post graduate resources available to help foster additional knowledge, we felt that a review article on the topic would be helpful.

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