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Differences in the Regulatory and Functional Effects of the Us3 Protein Kinase Activities of Herpes Simplex Virus 1 and 2
Journal of Virology, 10/26/09
Morimoto T et al. – The authors showed that alanine substitution in HSV–2 Us3 at a site corresponding to one that can be autophosphorylated in HSV–1 Us3 abolished HSV–2 Us3 kinase activity. Thus, the regulatory and functional effects of Us3 kinase activity are different between HSV–1 and HSV–2.
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