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Topical Antimicrobial Therapy for Treating Chronic Wounds
Clinical Infectious Diseases, 10/29/09
Lipsky BA et al. – There is controversy over how to treat poorly healing wounds with “secondary” signs suggesting infection; these may benefit from topical antimicrobial agents. Some evidence supports using topical agents for malodorous or burn wounds. Meta–analyses and systematic reviews suggest there are few proven indications for topical antimicrobials. Use of a newer, relatively nontoxic antiseptic is preferable to use of topical antibiotics, especially agents that are available for systemic use.
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