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See Latest ArticlesEffects of Chelators (Deferoxamine, Deferiprone and Deferasirox) on the Growth of Klebsiella Pneumoniae and Aeromonas Hydrophila Isolated from Transfusion-Dependent Thalassemia Patients
Hemoglobin, 10/23/09
Chan G C–F et al. – The growth of Klebsiella was marginally enhanced by DFO in vitro when compared to Yersinia. Such an unfavorable effect was not found in either L1 or deferasirox (DFRA) in vitro. The growth of Aeromonas was not affected by the presence of all three forms of chelators. Therefore, the authors suggest that factors other than DFO may account for the increased prevalence of Klebsiella and Aeromonas infection in Asian thalassemic patients.
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